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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR2 (Toll Like Receptor 2, Toll-like Receptor 2 Precursor, TLR 2, TLR-2, CD282, CD282 Antigen, Toll/interleukin 1 Receptor-like 4, Toll/interleukin Receptor-like Protein 4, TIL4) (PerCP)

Anti -TLR2 (Toll Like Receptor 2, Toll-like Receptor 2 Precursor, TLR 2, TLR-2, CD282,
CD282 Antigen, Toll/interleukin 1 Receptor-like 4, Toll/interleukin Receptor-like Protein
4, TIL4) (PerCP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Human Toll-Like receptor 2 (TLR2) is a 97kD, 766aa type I transmembrane glycoprotein of the Toll-like receptor family (TLR) of pattern recognition receptors. TLR2 is expressed on most leukocytes, endothelial cells and hepatocytes. It forms heterodimers with TLR1, TLR6, or in humans, TLR10, and recognizes lipoproteins and glycolipids from bacteria, mycoplasma, and yeast. Ligand recognition by TLR2 stimulates production of pro-inflammatory cytokines including TNF-a, IL-2, IL-6, IL-12, and MIP-2. The extracellular regions of human and mouse TLR2 share 67% aa identity.
Catalog #T8050-10C
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing PerCP conjugates will result in a substantial loss of activity. PerCP conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No9j13
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Peridinin-Chlorophyll-Protein-Complex (PerCP). Absorption: 482-564nm.
Emission675nm.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0 cells transfected with human TLR2 (Accession # O60603).
SpecificityRecognizes human TLR2. Species sequence homology: mouse (67%)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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