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Abs to Toll Like Receptors (TLR)
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Anti -TLR3 (Toll Like Receptor 3, Toll-like Receptor 3, TLR 3, TLR-3, CD283, CD283 Antigen)
Anti -TLR3 (Toll Like Receptor 3, Toll-like Receptor 3, TLR 3, TLR-3, CD283, CD283
Antigen)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
IP FC |
|
| TLR3 is a member of the Toll-like receptor (TLR) family and functions as a receptor for double-stranded (ds) RNA. TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents.They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity. | | | Catalog # | T8050-20P | | Applications | Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:10-1:50; 10ul labels 10e6 cells in 100ul | | Optimal dilutions to be determined by the researcher. | | Hybridoma | NS-1 myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10B1270 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified | | Immunogen | Ba/F3 cells transfected with human TLR3. | | Specificity | Recognizes human TLR3. Reported cell surface expression on MRC-5 fibroblasts and has been shown to suppress poly(1) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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