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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR3 (Toll-like Receptor 3, CD283) (PE)

Anti -TLR3 (Toll-like Receptor 3, CD283) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
Mouse TLR3 is a 100kD type I transmembrane protein that belongs to the mammalian toll-like receptor family of pattern recognition molecules. The extracellular region, which recognizes double-stranded RNA, contains 22 leucine-rich repeats. TLR3 is found intracellularly in a vesicular compartment and is not detected on the cell surface. The aa sequence of the mouse TLR3 extracellular domain is 90%, 79%, and 77% identical to that of rat, human, and bovine TLR3, respectively.
Catalog #T8050-24C
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaNSO myeloma cells from Balb/c mice.
Absorption 488nm
Emission 565-605nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No11n194
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to aa29-705 from mouse TLR3 expressed in NSO cells (NP_569054).
SpecificityRecognizes mouse TLR3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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