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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR6 (Toll Like Receptor 6, Toll-like Receptor 6 Precursor, CD286)

Anti -TLR6 (Toll Like Receptor 6, Toll-like Receptor 6 Precursor, CD286)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E FC
TLR6 is a ~105 kD cell surface type I transmembrane protein of the IL-1 receptor/Toll-like receptor (TLR) superfamily. TLRs are leucine-rich repeat-containing pattern recognition receptors for pathogen-associated molecular patterns that activate the innate immune system. TLR6 is expressed on macrophages, monocytes, neutrophils, and dermal endothelial cells in ligand-independent association with TLR-2. The mouse TLR6 extracellular domain shares 72%, and 86% aa identity with human and rat TLR6, respectively, and 59% aa with mouse TLR1.
Catalog #T8050-54A
ApplicationsSuitable for use in Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionFlow Cytometry: 25ug/ml. 10ul labels 1-2.5x10e5 cells in a total reaction volume 200ul. Tested using RAW 264.7 cells.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG2a
Clone No7H247
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenHEK293 cells transfected with mouse TLR6 (Accession # NP_035734)
SpecificityRecognizes mouse TLR6. Stains mouse TLR6 transfectants but not irrelevant transfectants.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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