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Abs to Toll Like Receptors (TLR)
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Anti -TLR10 (Toll-like Receptor 10, CD290, UNQ315/PRO358) (PE)
Anti -TLR10 (Toll-like Receptor 10, CD290, UNQ315/PRO358) (PE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). The cDNA for human TLR10 codes for a protein containing 811aa. Human TLR10 is closely related to human TLR1 and TLR6. TLR10 is expressed in tissues and cells of the immune system. | | | Catalog # | T8051-05N | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry (Intracellular): 2-3ug/10e6cells | | Optimal dilutions to be determined by the researcher. | | Positive Control | ThP1 | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11E378 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.05% sodium azide. Labeled with R-Phycoerythrin (PE). | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to extracellular domain of human TLR10. | | Specificity | Recognizes human TLR10. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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