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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR11 (Toll-like Receptor 11, Gm287)

Anti -TLR11 (Toll-like Receptor 11, Gm287)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IC IF
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
Catalog #T8051-10K
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 10g:ml
Western Blot: 0.5-2ug/ml
Immunocytochemistry: 10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlRAW264.7 cell lysates.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to murine TLR11.
SpecificityRecognizes mouse TLR11.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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