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Anti -TLR12 (Toll-like Receptor 12, Gm1365)
Anti -TLR12 (Toll-like Receptor 12, Gm1365)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
B |
|
| The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands. | | | Catalog # | T8051-21 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Transfected cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 11E379 | | Host | Mouse | | Source | Mouse | | Concentration | Not determined. | | Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide. | | Purity | Ascites | | Immunogen | Synthetic peptide corresponding to aa791-806 (LGLRLCLPERDFEPGK) of mouse TLR12; GenBank no ref NP_991392.1|. | | Specificity | Recognizes mouse TLR12. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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