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You are here:Home » Antibodies » Antibodies-Topoisomerases » Anti -Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha, DNA Topoisomerase II alpha Isozyme, TOP2, TOP2A, TP2A)

Anti -Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha, DNA Topoisomerase II alpha
Isozyme, TOP2, TOP2A, TP2A)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
DNA topoisomerase 2 catalyzes the transient breaking and rejoining of double stranded DNA during events such as DNA synthesis and transcription. Two forms of this enzyme exist, alpha and beta. DNA topoisomerase 2 alpha (TOP2A) is localized to chromosome 17 and the beta gene is localized to chromosome 3. At least 4 isoforms of TOP2A are produced by alternate splicing.
Catalog #T8065-12F
Suitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, 5% BSA, 0.05% Thimerosal, 0.05% sodium azide. Reconstitute with 100ul of sterile dH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1466-1480, RKPSTSDDSDSNFEK to human DNA topoisomerase 2-alpha.
SpecificityRecognizes human DNA topoisomerase 2-alpha at 174kD. Species Crossreactivity: rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDNA Topoisomerase 2-alpha, EC=, Topoisomerase (DNA) II alpha 170kDa

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