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You are here:Home » Antibodies » Abs to Topoisomerases » Anti -Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha, TOP2, TOP2A, TP2A)

Anti -Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha, TOP2, TOP2A, TP2A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Topo II Beta antibody plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is present ubiquitously in normal cells and is upregulated in tumors and proliferating cells. Further, it is implicated in drug resistance of tumor cells.
Catalog #T8065-21B
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenThis antibody maps to a region between residue 1475 and 1525 of human DNA Topoisomerase II Beta using the numbering given in entry NP_001059.2 (GeneID 7155).
SpecificitySpecies Crossreactivity: Human. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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