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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -TORC1, NT (CREB-regulated Transcription Coactivator 1, Transducer Of Regulated cAMP Response Element-binding Protein 1, TORC-1, Transducer of CREB Protein 1, Mucoepidermoid Carcinoma Translocated Protein 1, WAMTP1, MECT1, KIAA0616, CRTC1)

Anti -TORC1, NT (CREB-regulated Transcription Coactivator 1, Transducer Of Regulated cAMP
Response Element-binding Protein 1, TORC-1, Transducer of CREB Protein 1, Mucoepidermoid
Carcinoma Translocated Protein 1, WAMTP1, MECT1, KIAA0616, CRTC1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
TORC1 is the transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. It Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation and Enhances the interaction of CREB1 with TAF4. It regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.
Catalog #T8067-55C
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human TORC1 (KLH).
SpecificityRecognizes human TORC1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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