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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -TRAC-1 (T cell RING Activation Protein 1, TRAC 1, E3 Ubiquitin Protein Ligase RNF125, FLJ20456, MGC21737, Ring Finger Protein 125, RNF125, T-cell Ring Protein Identified in Activation Screen)

Anti -TRAC-1 (T cell RING Activation Protein 1, TRAC 1, E3 Ubiquitin Protein Ligase
RNF125, FLJ20456, MGC21737, Ring Finger Protein 125, RNF125, T-cell Ring Protein
Identified in Activation Screen)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B
TRAC-1 is a 232aa protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.
Catalog #T8169-32
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa100-150 of human TRAC-1.
SpecificityRecognizes human TRAC-1. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=6.3.2.-


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