Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to TRAF » Anti -TRAF2 Binding Protein (TRAF2-binding Protein, T2BP, Putative MAPK-activating Protein PM14, Putative NF-kappa-B-activating Protein 20, TRAF-interacting Protein with Forkhead-associated Domain, TRAF-interacting Protein with FHA Domain-containing Protein A,

Anti -TRAF2 Binding Protein (TRAF2-binding Protein, T2BP, Putative MAPK-activating Protein
PM14, Putative NF-kappa-B-activating Protein 20, TRAF-interacting Protein with
Forkhead-associated Domain, TRAF-interacting Protein with FHA Domain-containing Protein A,

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
T2BP, a novel 184aa protein, is human homolog of mouse Tifa. It consists of a central phosphopeptide-binding FHA domain and a C-terminal TRAF6-binding motif. T2BP mediates multiple protein-protein interactions and plays a significant role in innate immunity, adaptive immunity and inflammation. It interacts with TRAF2 and is involved in TNF-mediated signaling. It induces oligomerization and polyubiquitination of TRAF6 leading to activation of TAK1 and IKK in a proteasome-independent mechanism and mediates NF-kappaB and JNK activation. It enhances IRAK1/TRAF6 interactions and mediates IL-1 signaling suggesting a novel regulation of innate immunity and inflammation.
Catalog #T8171-96A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa150-162 of human T2BP, TIFA.
SpecificityRecognizes human TRAF2 Binding Protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links