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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -TRAF7 (TNF Receptor Associated Factor 7, TNF Receptor-associated Factor 7, TRAF 7, TRAF-7, DKFZp586I021, E3 Ubiquitin Protein Ligase TRAF7, MGC7807, Ring Finger and WD Repeat Domain 1, RFWD1, RING Finger Protein 119, RNF119)

Anti -TRAF7 (TNF Receptor Associated Factor 7, TNF Receptor-associated Factor 7, TRAF 7,
TRAF-7, DKFZp586I021, E3 Ubiquitin Protein Ligase TRAF7, MGC7807, Ring Finger and WD
Repeat Domain 1, RFWD1, RING Finger Protein 119, RNF119)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
TRAFs are signal transducers for members of TNFR superfamily. These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis. TRAF7, a novel 670aa protein, is a human homolog of mouse Traf7 and consists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus. It has E3-ubiquitin ligase activity for self-ubiquitination. TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways.It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and differentiation of hematopoietic cells.
Catalog #T8172-70A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 0.1-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa334-356 (ELKFDVLDENQSKLSEDLMEFRR) of human TRAF7.
SpecificityRecognizes human TRAF7. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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