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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -TRAM (TRIF-related Adapter Molecule, Putative NF-kappa-B-activating Protein 502, TIR Domain-containing Adapter Molecule 2, TICAM2, TICAM-2, Toll/interleukin-1 Receptor Domain-containing Protein, TIRP, Toll-like Receptor Adaptor Protein 3, TIRAP3)

Anti -TRAM (TRIF-related Adapter Molecule, Putative NF-kappa-B-activating Protein 502, TIR
Domain-containing Adapter Molecule 2, TICAM2, TICAM-2, Toll/interleukin-1 Receptor
Domain-containing Protein, TIRP, Toll-like Receptor Adaptor Protein 3, TIRAP3)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
TRAM, or TRIF-related adaptor molecule, plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-êB activation and cxcl10 promoter activity.
Catalog #T8190-01
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlLung Tissue Lysates
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa87-103 (EDDTDEALRVQNLLQDD) of human TRAM.
SpecificityRecognizes human TRAM. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMGC129876, MGC129877, Toll-like Receptor Adaptor Molecule 2


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