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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -TRAM (C2) (TRIF-related Adapter Molecule, Putative NF-kappa-B-activating Protein 502, TIR Domain-containing Adapter Molecule 2, TICAM2, TICAM-2, Toll/interleukin-1 Receptor Domain-containing Protein, TIRP, Toll-like Receptor Adaptor Protein 3, TIRAP3)

Anti -TRAM (C2) (TRIF-related Adapter Molecule, Putative NF-kappa-B-activating Protein
502, TIR Domain-containing Adapter Molecule 2, TICAM2, TICAM-2, Toll/interleukin-1
Receptor Domain-containing Protein, TIRP, Toll-like Receptor Adaptor Protein 3, TIRAP3)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IH
TIRP is a member of the Toll:interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, andultimately the activation of NF-kB. Expression of TIRP appears to be essential for TLR4 signalling.
Catalog #T8190-01A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry (paraffin): 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman (A), mouse (B), and rat (C) kidney cell lysates.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human TIRP (C2).
SpecificityRecognizes human TIRP (C2). Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMGC129876, MGC129877, Toll-like Receptor Adaptor Molecule 2


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