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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E

Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25mg/24h). Transferrin has a molecular weight of around 80kD and contains 2 specific high-affinity Fe(III) binding sites. The affinity of transferrin for Fe(III) is extremely high (1023M at pH 7.4) but decreases progressively with decreasing pH below neutrality.
Catalog #	T8199
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilutions	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	8.F.280
Host	Mouse
Source	Human
Concentration	~2mg/ml
Form	Supplied as a liquid in PBS, pH 7.0, 0.02% sodium azide.
Purity	Purified by Protein A affinity chromatography.
Immunogen	Purified human Transferrin
Specificity	Recognizes human Transferrin.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.