Anti -Transferrin (Transferin, TF, Apotransferrin, Beta-1 Metal-binding Globulin,
DKFZp781D0156, PRO1400, PRO1557, PRO2086, Serotransferrin Precursor, Siderophilin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH |
|
| Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 79.5kD and a serum concentration range of 1,800–2,700mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. | | | Catalog # | T8199-03 | | Applications | Suitable for use in ELISA, Immunohistochemistry and Functional Assays. Other applications not tested. | | Recommended Dilution | ELISA: 1:500- 1:5000. | | Immunohistochemistry (paraffin): 10ug/ml. Requires antigen retrieval using heat treatment prior to staining of paraffin sections using sodium citrate buffer, pH 6.0. | | Functional Assays: Removal of sodium azide is recommended. | | Optimal dilutions to be determined by the researcher. | | Positive Control Tissue | Placental villi | | Recommended Secondary Antibodies | I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo | | I1904-06H IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo | | I1904-14C: IgG, Fc (HRP) Pab Gt xMo | | I1904-19C: IgG, F(ab’)2 (HRP) Pab Gt xMo | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10B2492 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Human transferrin | | Specificity | Recognizes N-terminal domain of human transferrin. Inhibits the porliferation of Con-A stimulated blood lymphocytes in functional assays. Does not react with mouse, rabbit and bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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