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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -Transforming Growth Factor beta 1 (TGFb1)

Anti -Transforming Growth Factor beta 1 (TGFb1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
TGFb1 (transforming growth factor-beta1) is a family of multifunctional 25kD proteins. TGFb1 was originally identified for its ability to induce the growth of normal rodent fibroblasts in soft agar. It is now known that TGFb1 is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth, development and tissue remodeling following injury. TGFb1 is produced as latent high molecular weight complexes. The activation of latent TGFb1 is an important step in the regulation of its action.
Catalog #T8250-13A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000
Immunohistochemistry: 1:200-1:500
Optimal dilutions to be determined by the researcher
Recommended Positive ControlRAW264.7 cells (WB)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourcePorcine
Concentration~1mg/ml
FormSupplied as a liquid with 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenE. coli-expressed porcine TGFb1.
SpecificityRecognizes porcine TGFb1. Species Crossreactivity: human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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