Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Apoptosis » Anti -Transforming Growth Factor beta Receptor I (TGF beta Receptor I, TbetaR-I, TGF beta Receptor Type 1, TGF beta Type I Receptor, TGFBR1, TGFR1, TGFR-1, AAT5, Activin A Receptor Type II-like Kinase 53kDa, Activin Receptor-like Kinase 5, ALK5, ALK-5, ACVRLK4,

Anti -Transforming Growth Factor beta Receptor I (TGF beta Receptor I, TbetaR-I, TGF beta
Receptor Type 1, TGF beta Type I Receptor, TGFBR1, TGFR1, TGFR-1, AAT5, Activin A Receptor
Type II-like Kinase 53kDa, Activin Receptor-like Kinase 5, ALK5, ALK-5, ACVRLK4,

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and, in the kidney, they are found exclusively in renal tubular cells. In normal gastric mucosa, type I and II receptors are demonstrated in fundic glands, but not on surface mucous cells and in normal small bowel and colon, TGFB receptors are expressed in the epithelial cells of the upper crypts.
Catalog #T8250-31
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Paraffin): 1:25-1:50 Tryptic digestion of paraffin sections may enhance staining in some cases. Primary antibody incubation: 1hr at RT. Standard ABC technique for detection.
Immunohistochemistry: 1:10-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM,k
Clone No9F201
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid, 15mM sodium azide.
PuritySupernatant
ImmunogenProkaryotic recombinant protein corresponding to the external domain of the human transforming growth factor beta receptor type 1 molecule.
SpecificityRecognizes human Transforming Growth Factor beta Receptor I.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links