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You are here:Home » Molecular Biology » Growth Factors-TGF » Transforming Growth Factor beta 3, Recombinant, Mouse (TGFb3)

Transforming Growth Factor beta 3, Recombinant, Mouse (TGFb3)

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Specifications

Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
Catalog #T8250-45L
TGF-b3 Mouse Recombinant produced in E. coli is a disulfide-linked homodimeric, non-glycosylated, polypeptide chain containing 112 amino acids and having a molecular mass of 25,445 Dalton.
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn.
Biological Activity The ED50 as determined by the cell toxicity assay using the WHO Standard 98/608 as a direct comparison is < 0.05ng/ml corresponding to a specific activity of 20,000,000 Units/mg.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight25.445kD
SourceE. coli
FormSupplied as a liquid in 20% ethanol and 0.12% acetic acid.
Purity98% (SDS-PAGE)


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