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You are here:Home » Growth Factors, Cytokines » Growth Factors-TGF » Transforming Growth Factor beta Induced, 502-683aa, Recombinant, Human (BIGH3, TGFBI, ig-h3)

Transforming Growth Factor beta Induced, 502-683aa, Recombinant, Human (BIGH3, TGFBI,
ig-h3)

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Specifications

BIGH3, also known as TGFBI and Beta ig-h3, is an extracellular matrix protein induced by transforming growth factor(TGF)-beta 1. BIGH3 protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of BIGH3 were identified in families affected with human autosomal dominant corneal dystrophies. BIGH3 gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain). Recombinant human BIGH3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Catalog #T8252-90A
Endotoxin Level 1EU/ug (LAL)
Molecular Weight 19.9kD (182 aa)
Amino Acid SequenceMGTVMDVLKG DNRFSMLVAA IQSAGLTETL NREGVYTVFA PTNEAFRALP PRERSRLLGD AKELANILKY HIGDEILVSG GIGALVRLKS LQGDKLEVSL KNNVVSVNKE PVAEPDIMAT NGVVHVITNV LQPPANRPQE RGDELADSAL EIFKQASAFS RASQRSVRLA PVYQKLLERM KH
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight19.9kD
SourceE. coli
Purity95% by SDS-PAGE.
Concentration~0.5mg/ml
FormSupplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM EDTA, 0.1mM PMSF, 20% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBeta ig-h3, TGFBI, Kerato-epithelin, RGD-CAP


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