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You are here:Home » Antibodies » Abs to Proteins » Anti -Trefoil Factor 2 (Tff2, Sml1, Spasmolytic Polypeptide, SP)

Anti -Trefoil Factor 2 (Tff2, Sml1, Spasmolytic Polypeptide, SP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Trefoil factor 2 (TFF2), also known as spasmolytic polypeptide (Sp) is a 20kD secreted trefoil factor family protein. It is a protease-resistant glycoprotein primarily produced by mucous-secreting cells of the stomach and duodenum and is upregulated in response to inflammation. TFF2 interacts with mucin and other TFF2-binding proteins to protect and repair mucosal epithelium. TFF2 is also expressed by macrophages and lymphocytes and may have a role in modulating immune system responses. The 106 residue mature human TFF2 contains two trefoil domains (aa36-72 and aa80-121) and one N-linked glycosylation site. Human TFF2 shares 71-87aa sequence identity with canine and mouse TFF2, respectively.
Catalog #T8269-74E
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 15ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to internal domain of human TFF2 (KLH).
SpecificityRecognizes human TFF2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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