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Trichostatin A (TSA) (Histone Deacetylase Inhibitor)
Trichostatin A (TSA) (Histone Deacetylase Inhibitor)
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| 4,6-Dimethyl-7-[p-dimethylaminophenyl]-7-oxohepta-2, 4-dienohydroxamic acid. | | | Histone deacetylase inhibitor isolated from Streptomyces. | | | Catalog # | T8375-01 | | Inhibition of Histone Deacetylation | As shown with a previous lot, incubation of A431 cells with 50-100ng/ml Trichostatin A for 24 hours inhibited deacetylation of histones in vivo, as detected using anti-acetyl Histone H4. The optimal concentration of Trichostatin A should be empirically determined for the type of cells and assay used. | | CAS Number | 58880-19-6 | | Molecular Formula | C17H22N2O3 | | Molecular Weight | 302.37 | | Purity | > 98% by HPLC analysis. | | Form | Supplied as a powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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