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You are here:Home » Biochemicals » Biochem-Antibiotics » Trichostatin A

Trichostatin A


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Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6-methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.
Catalog #T8375-02
ApplicationsSuitable for use as a histone deacetylase inhibitor. Other applications have not been tested
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO or ethanol. Product reconstituted in DMSO is stable for 6 months at -20°C. Aliquot to avoid repeated freezing and thawing. Product reconstituted in ethanol is stable at 4ºC for 2-3 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number58880-19-6
Molecular FormulaC17H22N2O3
Molecular Weight302.4
SourceStreptomyces hygroscopicus
FormSupplied as a powder. Soluble in DMSO or ethanol
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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