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You are here:Home » Antibodies » Abs to Transcription Factors, TRIM (Tripartite Motif) » Anti -TRIM37 (E3 Ubiquitin-protein Ligase TRIM37, Mulibrey Nanism Protein, Tripartite Motif-containing Protein 37, KIAA0898, MUL, POB1)

Anti -TRIM37 (E3 Ubiquitin-protein Ligase TRIM37, Mulibrey Nanism Protein, Tripartite
Motif-containing Protein 37, KIAA0898, MUL, POB1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified.
Catalog #T8466-37G
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:64,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to EDLSFNTDENSGR, from the C-terminus of the protein sequence according to NP_056109.
SpecificityRecognizes TRIM37. Species sequence homology: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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