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You are here:Home » Biochemicals » Biochem-Antibiotics » Trinactin (Antibiotic AKD-1D, Antibiotic S 3466B)

Trinactin (Antibiotic AKD-1D, Antibiotic S 3466B)


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Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp. Early literature reported that trinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibited T-cell proliferation induced by IL-2 and cytokine production at nonomolar levels for IL-2, IL-4, IL-5 and interferon-gamma. Trinactin has not previously been available for intensive investigation.
Catalog #T8470
Purity >95% by HPLC
Solubility Soluble in ethyl acetate or DMSO, moderately in soluble ethanol or methanol.
Related to Monactin, Dinactin
CAS Number7561-71-9
Molecular FormulaC43H70O12
Molecular Weight779
SourceStreptomyces sp.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAntibiotic AKD-1D, Antibiotic S 3466B

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