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Abs to Receptors, Tyrosine Kinase
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Anti -TrkA, Phosphorylated (Tyr490) (High Affinity Nerve Growth Factor Receptor, Neurotrophic Tyrosine Kinase Receptor Type 1, TRK1-transforming Tyrosine Kinase Protein, Tropomyosin-related Kinase A, Tyrosine Kinase Receptor, Tyrosine Kinase Receptor A, Trk-A,
Anti -TrkA, Phosphorylated (Tyr490) (High Affinity Nerve Growth Factor Receptor,
Neurotrophic Tyrosine Kinase Receptor Type 1, TRK1-transforming Tyrosine Kinase Protein,
Tropomyosin-related Kinase A, Tyrosine Kinase Receptor, Tyrosine Kinase Receptor A, Trk-A,
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IC |
|
| TrkA, the high affinity Nerve Growth Factor (NGF) receptor, autophosphorylates on tyrosine to activate multiple effectors. Phosphorylation at Tyr490 is required for Shc association and activation of the Ras-MAP kinase cascade. Residues Tyr674/675 lie within the catalytic domain, and phosphorylation at these sites reflects Trk kinase activity. | | | Catalog # | T8663-04E | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1ug/ml | | Immunoprecipitation: 4-8ug/ml | | Immunocytochemistry: 10-20ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to Tyr490 from human TrkA. | | Specificity | Recognizes human Phospho-TrkA at ~140kD. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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