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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF, NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B, Ntrk2, Trkb)

Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF, NT-3 growth factors receptor, Neurotrophic
tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B, Ntrk2,
Trkb)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Catalog #T8663-20K
Catalytic activity ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures (By similarity). Binds APS. Interacts with SQSTM1.
ApplicationsSuitable for use in Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: 1:1000-1:3000
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstiutute with 100ul sterile water.
PuritySerum
ImmunogenSynthetic peptide (AFPRLEPNSIDPENC) as part of rat mature TrkB protein (aa 23-36) conjugated to KLH.
SpecificityRecognizes human and rat TrkB. Does not crossreact with TrkA and TrkC.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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