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Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B) (Ntrk2)
Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic
tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B)
(Ntrk2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E IH |
|
| TrkB is a member of the neurotrophic tyrosine receptor kinase family. It is a membrane-bound receptor and upon neurotrophin binding, it phosphorylates itself as well as MAPK pathways members. TrkB is the receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). It is Involved in the development and/or maintenance of the nervous system. | | | Catalog # | T8663-20L | | Subunit | Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | ELISA: 1:10,000 | | Immunohistochemistry: 1:1,000-1:3,000 dilution used to stain frozen sections of rat peripheral sensory ganglia | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | Not determined | | Form | Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O. | | Purity | Serum | | Immunogen | Extracellular domain of glycosylated mouse TrkB protein produced in CHO cells. Cellular localization: Membrane; single-pass type I membrane protein. | | Specificity | Recognizes rat and mouse TrkB. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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