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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B) (Ntrk2)

Anti -TrkB (Tyrosine Kinase Receptor B) (BDNF/NT-3 growth factors receptor, Neurotrophic
tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B)
(Ntrk2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E IH
TrkB is a member of the neurotrophic tyrosine receptor kinase family. It is a membrane-bound receptor and upon neurotrophin binding, it phosphorylates itself as well as MAPK pathways members. TrkB is the receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). It is Involved in the development and/or maintenance of the nervous system.
Catalog #T8663-20L
Subunit Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures.
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsELISA: 1:10,000
Immunohistochemistry: 1:1,000-1:3,000 dilution used to stain frozen sections of rat peripheral sensory ganglia
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
PuritySerum
ImmunogenExtracellular domain of glycosylated mouse TrkB protein produced in CHO cells. Cellular localization: Membrane; single-pass type I membrane protein.
SpecificityRecognizes rat and mouse TrkB.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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