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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -Tyrosine Kinase Receptor C (TrkC)(NT-3 growth factor receptor, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, GP145-TrkC, Trk-C)

Anti -Tyrosine Kinase Receptor C (TrkC)(NT-3 growth factor receptor, Neurotrophic tyrosine
kinase receptor type 3, TrkC tyrosine kinase, GP145-TrkC, Trk-C)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
TrkC is a member of the neurotrophic tyrosine receptor kinase family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3). Â Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position.
Catalog #T8663-23C
ApplicatonsSuitable for use in Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: 1:1000 -1:3000
Optimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.
PuritySerum
ImmunogenExtracellular domain of glycosylated human TrkC protein produced in CHO cells. Cellular localization: Membrane; single-pass type I membrane protein.
SpecificityRecognizes Tyrosine Kinase Receptor C. Species crossreactivity: human, rat, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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