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Abs to Receptors, Tyrosine Kinase
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Anti -Tyrosine Kinase Receptor C (TrkC)(NT-3 growth factor receptor, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, GP145-TrkC, Trk-C)
Anti -Tyrosine Kinase Receptor C (TrkC)(NT-3 growth factor receptor, Neurotrophic tyrosine
kinase receptor type 3, TrkC tyrosine kinase, GP145-TrkC, Trk-C)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| TrkC is a member of the neurotrophic tyrosine receptor kinase family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3). Â Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. | | | Catalog # | T8663-23C | | Applicatons | Suitable for use in Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry: 1:1000 -1:3000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | | | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O. | | Purity | Serum | | Immunogen | Extracellular domain of glycosylated human TrkC protein produced in CHO cells. Cellular localization: Membrane; single-pass type I membrane protein. | | Specificity | Recognizes Tyrosine Kinase Receptor C. Species crossreactivity: human, rat, mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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