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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -Troponin C, Cardiac (Cardiac Troponin C, CMH7, cTnI, Slow Troponin C1, Troponin C Slow, Troponin C Slow Skeletal and Cardiac Muscles, TN C, TNC, TN-C, TNNC, Troponin C Type 1 (Slow), Troponin C1 Slow, TNNC 1, TNNC1, TNNC1 Protein, Troponin I Type 3 (Cardi

Anti -Troponin C, Cardiac (Cardiac Troponin C, CMH7, cTnI, Slow Troponin C1, Troponin C
Slow, Troponin C Slow Skeletal and Cardiac Muscles, TN C, TNC, TN-C, TNNC, Troponin C Type
1 (Slow), Troponin C1 Slow, TNNC 1, TNNC1, TNNC1 Protein, Troponin I Type 3 (Cardi

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: TnI which is the inhibitor of actomyosin ATPase, TnT which contains the binding site for tropomyosin and TnC. The binding of calcium to TnC abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium ion uptake by troponin C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
Catalog #T8665-01A
ApplicationsSuitable for use in ELISA, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No9F114
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenHuman cardiac troponin C
SpecificityRecognizes human Troponin C at ~19kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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