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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -Troponin C (Troponin C, slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC) (Azide Free)

Anti -Troponin C (Troponin C, slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC) (Azide
Free)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Catalog #T8665-01D
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionsELISA: 1ug/ml-3ng/ml
Immunohistochemistry (paraffin): 1.5ug/ml
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C911
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to full human Troponin C (corresponding to a portion of amino acids within aa1-162, AAH30244) with a GST tag. The MW of the GST tag alone is 26kD.
SpecificityRecognizes human Troponin C.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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