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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -Troponin I, Cardiac (Cardiac Troponin I, Troponin I Cardiac Muscle, cTnI, TNNC1, CMD1FF, CMD2A, CMH7, MGC116817, RCM1, TNNI3)

Anti -Troponin I, Cardiac (Cardiac Troponin I, Troponin I Cardiac Muscle, cTnI, TNNC1,
CMD1FF, CMD2A, CMH7, MGC116817, RCM1, TNNI3)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP
Troponin I is a 24kD subunit of Troponin, a protein found on muscle tissue responsible for muscle contraction. When calcium binds to Troponin C, a conformational change moves Troponin I and tropomyosin out of the way of the myosin binding sites on the actin filaments in muscles. This allows cross­bridging to occur and the muscle to contract. Levels of cTnI in serum are commonly used as a marker for cardiac cell damage and death.
Catalog #T8665-15G
ApplicationsSuitable for use in ELISA, Immunoprecipitation and Western Blot. Other applications have not been tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No596
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMixture of free human cardiac Troponin I and native human cardiac Troponin complex.
SpecificityRecognizes an epitope between aa 69-178 of human cardiac Troponin I (cTnI). Does not cross react with skeletal TnI.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTroponin I Type 3 (Cardiac)


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