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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -Troponin T, Cardiac (cTnT)

Anti -Troponin T, Cardiac (cTnT)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Troponin T is a thin filament regulatory protein of striated muscle that binds to troponin C and I to tropomyosin and is required for calcium-dependent ATPase activity of myofibrillar proteins. It is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. This expression in the human heart is affected by heart failure.
Catalog #T8665-22A
ApplicationsSuitable for use in ELISA, Western Blot and Immunoaffinity Purification. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Matched PairSuitable for use as the capture or solid phase antibody. Matched to T8665-22B as the detection or conjugate (label) antibody.
Also suitable for use as the detection or conjugate (label) antibody. Matched to T8665-22C as the capture or solid phase antibody.
HyrbidomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No1.BB.154
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenFree human Cardiac Troponin T.
SpecificityRecognizes human Cardiac Troponin T. Recognizes an epitope located betweeen aa95-181. Species Crossreactivity: mouse, rat and canine. Does not crossreact with human skeletal Troponin T.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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