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You are here:Home » Antibodies » Antibodies-Cardiac Markers » Anti -Troponin T, Cardiac (cTnT)

Anti -Troponin T, Cardiac (cTnT)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Troponin T is a thin filament regulatory protein of striated muscle that binds to troponin C and I and to tropomyosin and is required for calcium-dependent ATPase activity of myofibrillar proteins. It is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. This expression in the human heart is affected by heart failure.
Catalog #T8665-22C
ApplicationsSuitable for use in ELISA, Immunoaffinity Purification and Western Blot. Other applications have not been tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Matched PairsCapture: T8665-22C, T8665-22C
Detection: T8665-22B, T8665-22A
Suitable for use as the capture or solid phase antibody.
Matched to T8665-22A, T8665-22B or T8665-30A as the detection or conjugate (label) antibody.
HybridomaHybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No1.BB.157
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenFree human cardiac Troponin T
SpecificityRecognizes human cardiac Troponin T. Recognizes an epitope between aa60-70. Does not crossreact with human skeletal Troponin T. Species Crossreactivity: Bovine and chicken. Does not react with canine, feline, fish, porcine, mouse, goat, rabbit or rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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