You are here:Home
»
Antibodies
»
Abs to Disease Markers
»
Anti -TSG101 (Tumor Susceptibility Gene 101, Tumor Susceptibility Gene 101 Protein, TSG 101, TSG-101, TSG10, Tumor Susceptibility Protein Isoform 3, VPS23)
Anti -TSG101 (Tumor Susceptibility Gene 101, Tumor Susceptibility Gene 101 Protein, TSG
101, TSG-101, TSG10, Tumor Susceptibility Protein Isoform 3, VPS23)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IH IF |
|
| The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phospho-protein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. | | | Catalog # | T9101-75 | | Applications | Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunoprecipitation: 0.5-2ug/ml | | Western Blot: 1:500-1:2000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Molt 4 and HeLa cell lysates. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 9F347 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4. No preservatives added. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | A fusion protein containing residues 167-374 of human TSG101 protein. | | Specificity | Recognizes human TSG101. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
