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You are here:Home » Antibodies » Abs to Tubulin » Anti -Tubulin, beta 3 (Tubulin beta III, Tubulin beta 3 Chain, TUBB 3, TUBB3, Neuron Specific beta III Tubulin, beta-4, MC1R, Tubulin beta 4, TUBB 4, TUBB4)

Anti -Tubulin, beta 3 (Tubulin beta III, Tubulin beta 3 Chain, TUBB 3, TUBB3, Neuron
Specific beta III Tubulin, beta-4, MC1R, Tubulin beta 4, TUBB 4, TUBB4)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
Dimers of alpha and beta tubulin bind to two GTP molecules and assemble into microtubules. The GTP bound to the beta tubulin subunit eventually hydrolyses into GDP. This GTP cycle is essential for microtubule stability, as dimers bound to GTP tend to assemble into microtubules, whereas dimers bound to GDP tend to be unstable. The tubulin beta 3 chain (also known as neuron-specific class III beta-tubulin) are found exclusively in neurons and serves as a neuronal marker. It has also been found in cancer cells and correlates with an increasing histological degree of malignancy.
Catalog #T9155-03H
ApplicationsSuitable for use in Western Blot and Immunohistochemistry (frozen, paraffin). Other applications not tested.
Recommended DilutionWestern Blot: 1:10,000
Immunohistochemistry (paraffin, frozen): 1:1,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9j4
HostMouse
SourceRat
ConcentrationNot determined
FormSupplied as a liquid in10mM HEPES, pH 7.5, 150mM sodium chloride, 0.01% BSA, 50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to Tubulin Beta 3.
SpecificityRecognizes rat tubulin beta 3. Species sequence homology: broad.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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