Anti -Tumor Necrosis Factor Receptor Associated Factor 3 (TNF Receptor Associated Factor
3, TNF Receptor-associated Factor 3, TRAF 3, TRAF3, TRAF-3, CD40-associated Protein 1,
CAP1, CAP-1, CD40 Binding Protein, CD40 BP, CD40BP, CD40 Receptor-associated Factor 1
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IP |
|
| MIP-T3 (microtubule-interacting protein associated with TRAF3) was originally identified in a yeast-two hybrid screen for proteins that interact with the tumor necrosis factor receptor (TNFR)-associated factor 3 (TRAF3). As a microtubule binding protein, MIP-T3 has been found to mediate the binding of DISC1 (disrupted-in-schizophrenia 1) to microtubules. MIP-T3 has also been shown to associate with IL13 receptor alpha (IL-13Ralpha1) and function as an inhibitor of IL-13 signaling. Recently, studies of the C. elegans homolog of MIP-T3 (DYF-11) have revealed that MIP-T3 is critical to cilium development; and in mammalian cells, MIP-T3 has been found to localize to basal bodies and cilia. Alternate names for MIP-T3 include TRAF3IP1, interleukin13 receptor alpha1-binding protein 1, and TRAF3-interacting protein. | | | Catalog # | T9161-56L | | Applications | Suitable for use in Immunoprecipitation. Not recommended for Western Blot analysis. Other applications not tested. | | Recommended Dilution | Immunoprecipitation: 2-5ug/mg lysate | | Optimal dilution determined by the researcher. | | | | Storage and Stability: | | May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 3 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1 mg/ml | | | Form | Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7 to 8, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized by this antibody maps to a region between residue 550 and 600 of human microtubule interacting protein that associates with TNF receptor-associated factor 3. | | Specificity | Recognizes human TRAF-3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Tumor Necrosis Factor Receptor Associated Factor 3 (TNF Receptor Associated Factor 3, TNF Receptor-associated Factor 3, TRAF 3, TRAF3, TRAF-3, CD40-associated Protein 1, CAP1, CAP-1, CD40 Binding Protein, CD40 BP, CD40BP, CD40 Receptor-associated Factor 1 |
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