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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -TRAF2 (TNF Receptor-associated Factor 2, E3 Ubiquitin-protein Ligase TRAF2, Tumor Necrosis Factor Type 2 Receptor-associated Protein 3, TRAP3)

Anti -TRAF2 (TNF Receptor-associated Factor 2, E3 Ubiquitin-protein Ligase TRAF2, Tumor
Necrosis Factor Type 2 Receptor-associated Protein 3, TRAP3)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
TRAF2 is a 52kD protein which binds directly to TNF receptors and other TRAF proteins, transducing apoptotic and stress response signal cascades through adaptors including inhibitor of apoptosis proteins (IAPs). TRAF2 can also bind TNF receptors by forming a heterodimeric complex with TRAF1. Additionally TRAF2 forms a stronger, indirect, association with TNF receptors by forming a complex with apoptotic signal transducer (Tumor necrosis factor receptor associated death domain).
Catalog #T9161-71B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No33A1293
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to aa205-222 of human TRAF2.
SpecificityRecognizes human TRAF2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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