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Anti -TSC2 (Tuberous Sclerosis 2 Protein, TSC4, Tuberin)
Anti -TSC2 (Tuberous Sclerosis 2 Protein, TSC4, Tuberin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| TSC2 is important in regulating cell proliferation and tumor development. Mutations in either the TSC1 or TSC2 tumor suppressor genes caused tuberous sclerosis complex (TSC), an autosomal dominant tumor syndrome. Tuberin is a product of the TSC2 tumor suppressor gene. Tuberin form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR). | | | Catalog # | T9170-04B | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1-4ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to region surrounding aa548 of rat TSC2. | | Specificity | Recognizes TSC2 rat. Species Crossreactivity: human and mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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