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Abs to 14-3-3
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Anti -Tyrosine 3/Tryptophan 5-Monooxygenase Activation Protein epsilon (14-3-3 epsilon, Mitochondrial Import Stimulation Factor L, Protein Kinase C Inhibitor Protein 1, YWHAE)
Anti -Tyrosine 3/Tryptophan 5-Monooxygenase Activation Protein epsilon (14-3-3 epsilon,
Mitochondrial Import Stimulation Factor L, Protein Kinase C Inhibitor Protein 1, YWHAE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Chicken |
Affinity Purified |
E B |
|
| This protein belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. | | | Catalog # | T9247-85A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000-1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgY | | Host | Chicken | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1-255 of human Tyrosine 3/Tryptophan 5-Monooxygenase Activation Protein epsilon. | | Specificity | Reconizes human Tyrosin 3/Tryptophan 5-Monooxygenase Activation Protein epsilon. Species Crossreactivity: mouse, rat and bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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