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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -Uncoupling Protein 1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, Ucp1, Ucp, AI385626, Solute Carrier Family 25 Member 7, Slc25a7, Thermogenin)

Anti -Uncoupling Protein 1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, Ucp1,
Ucp, AI385626, Solute Carrier Family 25 Member 7, Slc25a7, Thermogenin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
UCP1 gene encodes a unique mammalian mitochondrial proton carrier that induces heat production in brown adipose tissue by uncoupling respiration from ATP synthesis. Despite its tissue specificity, UCP1 is a member of the mitochondrial carrier protein family, which includes the ATP/ADP translocator, the phosphate, the 2-oxoglutarate/malate and the citrate (tricarboxylate) carriers. Like other mitochondrial carriers, UCP1 is inserted into the inner mitochondrial membrane by means of six alpha-helical hydrophobic domains, each encoded by one of the six exons. In humans, polymorphism in UCP1 gene has been associated with a number of measures of glucose homeostasis and adiposity. Mouse UCP1 gene is located in the chromosomal region 8 38.0 cM.
Catalog #U1620-07A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa288-304 (CFEQLKKELMKSRQTVD) of mouse UCP1.
SpecificityRecognizes mouse UCP1. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesUncoupling Protein 1 (Mitochondrial, Proton Carrier)


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