Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -Uncoupling Protein 1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, UCP1, UCP-1, UCP, HGNC:12517, Solute Carrier Family 25 Member 7, SLC25A7, Thermogenin)

Anti -Uncoupling Protein 1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, UCP1,
UCP-1, UCP, HGNC:12517, Solute Carrier Family 25 Member 7, SLC25A7, Thermogenin)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Mitochondrial brown fat uncoupling protein 1 (UCP1; also Thermogenin and UCP) is a 33kD member of the mitochondrial carrier family of proteins. Human and mouse UCP1 are both 307aa in length and contain three solcar repetitive regions and six transmembrane segments. UCP1 is found in brown adipose tissue, where it becomes activated by fatty acids and inhibited by nucleotides. It functions as a mitochondrial transporter that creates a proton leak across the inner mitochondrial membrane, uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. Human and mouse UCP1 share 79% aa sequence identity.
Catalog #U1620-08B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.1-1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Adipose lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-EQLKRELSKSRQ, from the C-terminus of the protein sequence according to NP_068605.1.
SpecificityRecognizes human UCP1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesUncoupling Protein 1 (Mitochondrial, Proton Carrier)


External Links