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Anti -Uncoupling Protein 1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, UCP1, UCP-1, UCP, HGNC:12517, Solute Carrier Family 25 Member 7, SLC25A7, Thermogenin)
Anti -Uncoupling Protein 1 (Mitochondrial Brown Fat Uncoupling Protein 1, UCP 1, UCP1,
UCP-1, UCP, HGNC:12517, Solute Carrier Family 25 Member 7, SLC25A7, Thermogenin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| UCP1 is a 32kD protein that is active as a proton channel-forming dimmer. It can bind purine nucleotides and is capable of being stimulated by fatty acids. UCP1 is exclusively expressed in brown adipose tissue (BAT) in rodents and in neonates where it is regulated by norepinephrine and thyroid hormones. | | | Catalog # | U1620-08D | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1-2ug/ml for 2h at RT | | Immunohistochemistry (Formalin fixed paraffin embedded): 1:50 for 10min at RT | | Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20min | | Optimal dilutions to be determined by the researcher. | | Positive Control | Rh-30 cells, brown adipose | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the aa145-159 of human UCP1. | | Specificity | Recognizes human UCP1. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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