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You are here:Home » Antibodies » Antibodies-Obesity Proteins » Anti -Uncoupling Protein 3 (UCP 3, UCP3, Mitochondrial Uncoupling Protein 3, Solute Carrier Family 25 Member 9, SLC25A9)

Anti -Uncoupling Protein 3 (UCP 3, UCP3, Mitochondrial Uncoupling Protein 3, Solute
Carrier Family 25 Member 9, SLC25A9)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
UCP3 is a recently identified candidate mediator of adaptive thermogenesis in humans. It is expressed predominantly in human skeletal muscle and heart and exists as short and long form transcripts, UCP3S and UCP3L. UCP3 is thought to uncouple oxidative phosphorylation, reducing aerobic ATP production and dissipating energy as heat and thus plays an important role in the regulation of human energy expenditure. The protein is also involved in the exit of fatty acids out of the mitochondrial matrix, insulin sensitivity and protection against both reactive oxygen species. The pathological role of the protein has been studied in severe obesity. The human UCP3 gene is localized in the chromosomal region 11q13.
Catalog #U1622-03B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman, mouse and rat heart lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa125-175 of human UCP3.
SpecificityRecognizes human UCP3. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesUncoupling Protein 3 (Mitochondrial, Proton Carrier)

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