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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -Uncoupling Protein 3 (UCP 3, UCP3, Mitochondrial Uncoupling Protein 3, Solute Carrier Family 25 Member 9, SLC25A9)

Anti -Uncoupling Protein 3 (UCP 3, UCP3, Mitochondrial Uncoupling Protein 3, Solute
Carrier Family 25 Member 9, SLC25A9)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The uncoupling protein UCP1 (formally designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimmer that acts as a protein channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP3 is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
Catalog #U1622-03C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml for 2h at RT
Optimal dilutions to be determined by the researcher.
Positive ControlSkeletal muscle
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.0, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-terminal of human UCP3.
SpecificityRecognizes human UCP3. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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