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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified E B IH

Uncoupling Protein 3 (UCP3), human. It is expected that the antibody will recognize both the long and short forms (30–33kD & 24–27kD) however splice variants are expected and precise reactivity profile has yet to be determined. Human UCP3 long form (UCP3L) is a 312 aa mitochondrial uncoupling protein (1,2). It is only 57% and 73% homologous with human UCP1 and UCP2 respectively. Like other UCPs, UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and is only 275 aa long (2). UCP3 has preferential expression in muscle and it is unaffected by cold acclimation.
Catalog #	U1622-10
Applications	Western Blotting: 1–10mg/ml using Chemiluminescence technique. Immunohistochemistry: 2–20mg/ml on formaldehyde fixed tissue. ELISA: (1:10,000–1:100,000 using 50–100ng UCP32 control peptide/well).
CAS Number	n/a
Clone Type	Polyclonal
Host	Rabbit
Source	Human
Concentration	~0.5mg/ml
Form	Supplied as a liquid in PBS, pH 7.4 with 0.1% BSA as stabilizer and 0.02% sodium merthiolate
Purity	Affinity purified Ig
Immunogen	14 amino acid peptide sequence (designated UCP32) mapping near the C-terminus of human UCP3 (1)
Specificity	The UCP32 peptide has no significant homology with UCP1 or UCP2. The antibody has not yet been tested for crossreactivity to other species. The sequence used for immunization shows 93% homology to mouse UCP3.
Important Note	This product is intended for research use only, not for use in human, therapeutic or diagnostic applications.