Anti -Urotensin II Receptor (UR-II-R, Urotensin 2 Receptor, Urotensin-2 Receptor, UR-2-R,
UTR2, UTR, UTS2R, G-protein Coupled Receptor 14, GPR14)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| UII-R, initially named GPR14, is a Urotensin Receptor that binds urotensin-II (U-II) and regulates cardiovascular function. Urotensin-II receptor has been reported to be expressed at high levels in the heart and pancreas and also in artery and smooth muscle. Low transcript levels have been identified in brain, particularly in thalamus, superior occipital gyrus, and substantia nigra. ESTs have been isolated from fetal, melanocyte/uterus/fetal heart, and ovarian thecoma fibroma libraries. | | | Catalog # | U2800-10B | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 6-11ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Rat Pancreas, Acinar epithelium | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the 3rd cytoplasmic domain of human GPR14. | | Specificity | Recognizes GPR14. Species Crossreactivity: rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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