Anti -USP7 (USP-7, USP 7, Ubiquitin Specific Processing Protease 7, HAUSP, Herpers
Virus-associated Ubiquitin-specific Protease, Deubiquitinating Enzyme 7, Ubiquitin
Thiolesterase 7, Ubiquitin Carboxyl-terminal Hydrolase 7, TEF1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH IF |
|
| USP7 (also called HAUSP) is a de-ubiquitinating enzyme recently identified as a key regulator of the p53-mdm2 pathway, which stabilizes both p53 and mdm2. The Epstein-Barr nuclear antigen 1 protein of Epstein-Barr virus binds with high affinity to USP7 and disrupts the USP7-p53 interaction. | | | Catalog # | U4100-02 | | Applications | Suitable for use in ELISA, Immunofluorescence, Western Blot and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | | | Immunohistochemistry (Paraffin): 5ug/ml | | Western Blot: 1:500-1:2000 | | ELISA: 1:15,000-1:60,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa30-41 of human USP7 (KLH). | | Specificity | Recognizes human Ubiquitin Specific Protease 7 (herpes Virus-associated) (USP7). Species Crossreactivity: bovine, chimpanzee, chicken, canine, mouse, rat and zebrafish. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=3.1.2.15 |
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