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You are here:Home » Molecular Biology » MB-Enzymes, Substrates » USP14 Inhibitor, IU1 (1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone)

USP14 Inhibitor, IU1


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A cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC50=4-5uM). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34uM.
Catalog #U4100-49
Sequence1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1- pyrrolidinyl)-ethanone
SolubilityDMSO (20mg/ml)
Molecular Weight~300.37
CAS Number314245-33-5
Molecular FormulaC H FN O
Molecular Weight~300.37
Purity~98% (HPLC)
ConcentrationNot determined
FormSupplied as a white to off-white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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