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USP14 Inhibitor, IU1 (1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone)
USP14 Inhibitor, IU1
(1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone)
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| A cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC50=4-5uM). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34uM. | | | Catalog # | U4100-49 | | Sequence | 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1- pyrrolidinyl)-ethanone | | Solubility | DMSO (20mg/ml) | | Molecular Weight | ~300.37 | | CAS Number | 314245-33-5 | | Molecular Formula | C H FN O | | Molecular Weight | ~300.37 | | Purity | ~98% (HPLC) | | Concentration | Not determined | | Form | Supplied as a white to off-white solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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